PHASE 1Life Biosciences ER-100 — first-ever partial epigenetic reprogramming in humans, FDA-cleared Jan 2026PHASE 1Retro Biosciences RTR242 — first-in-human dose Adelaide Dec 2025, AI-designed Yamanaka variantsCAPITALAltos Labs $3B preclinical, Sentinel Cell program 2026PHASE 2Intervene Immune TRIIM-X enrolling — 2.5yr biological age reversal in original 9-man trialSIGNALBuck Institute 2025: TPE+IVIG cut biological age 2.61 years on multi-omic clocksREGFDA Category 2 on BPC-157 — most peptide compounding restricted 2024-2025RXSELECT trial: semaglutide cut cardiovascular events 20% in non-diabeticsFRONTIERStem Cell Institute Panama — 'Golden Cells' umbilical cord MSCs, no FDA jurisdictionPHASE 1Life Biosciences ER-100 — first-ever partial epigenetic reprogramming in humans, FDA-cleared Jan 2026PHASE 1Retro Biosciences RTR242 — first-in-human dose Adelaide Dec 2025, AI-designed Yamanaka variantsCAPITALAltos Labs $3B preclinical, Sentinel Cell program 2026PHASE 2Intervene Immune TRIIM-X enrolling — 2.5yr biological age reversal in original 9-man trialSIGNALBuck Institute 2025: TPE+IVIG cut biological age 2.61 years on multi-omic clocksREGFDA Category 2 on BPC-157 — most peptide compounding restricted 2024-2025RXSELECT trial: semaglutide cut cardiovascular events 20% in non-diabeticsFRONTIERStem Cell Institute Panama — 'Golden Cells' umbilical cord MSCs, no FDA jurisdiction
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